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Anti-E2F1 Polyclonal Antibody 一抗

Anti-E2F1 Polyclonal Antibody 一抗

型    号: K003190P
报    价:
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Anti-E2F1 Polyclonal Antibody 一抗
英文名称:Rabbit E2F1 Polyclonal Antibody
克隆类型:Polyclonal Antibody
应用:WB,IHC
稀释比例:WB1:500-1:1000 IHC1:50-1:200
交叉反应:Human Mouse

K003190PAnti-E2F1 Polyclonal Antibody 一抗的详细资料:

Anti-E2F1 Polyclonal Antibody 一抗
品牌:Solarbio 
货号:K003190P
商品货号:       商品品牌:    规格                   
K003190P-50ul    Solarbio      50ul         
K003190P-100ul   Solarbio     100ul
英文名称:Rabbit E2F1 Polyclonal Antibody
应用2:WB IHC
克隆类型2:Polyclonal Antibody
别名:E2F-1;RBAP1;RBBP3;RBP3 
应用:WB,IHC
稀释比例:WB1:500-1:1000 IHC1:50-1:200
交叉反应:Human Mouse
蛋白分子量:47kDa
Gene ID:1869
保存:Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
储存液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法:Affinity purification
亚型:IgG
免疫原:A synthetic peptide of human E2F1
性状:Lyophilized or Liquid
Swiss Prot:Q01094
克隆类型:Polyclonal Antibody
来源:Rabbit
背景资料:The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can te both cell proliferation and p53-dependent/independent apoptosis.


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